Aww shit - unfortunately it does not work with everything. Here's the list of games which doesn't work properly with custom vu-skip:

Dragon Quest VIII - blue screen - reported by ilya6681
Final Fantasy X International UNDUB NTSC-J - invisible 3D graphics (PAL version does work lol)
Final Fantasy XII PAL - invisible 3D graphics
Kingdom Hearts NTSC - invisible 3D graphics
Manhunt 2 PAL - black screen - reported by Player 1
Naruto Ultimate Ninja and Accel series - black - reported by mugenamarv & Brahim
Persona 3 - reported by user24687
Rengou vs Zaft II Plus NTSC-J - doesn't work in 2 player mode - half of the screen is black <means u can see everything while ur partner can't see a shit lol; all single player modes work perfect, though>
Resident Evil 4 PAL - invisible 3D graphics
Soul Calibur 3 NTSC - black screen - reported by Player 1
Tekken 4/5 Polygons/Field of View bugs - reported by Buratino
Xenosaga Ep. III - invisible 3D graphics - reported by oswald

Please report non-working ones in the comments of the file.